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本文报道了斯德哥尔摩直肠癌研究组总结13个机构在1980～1987年中,对849名可切除直肠腺癌病人行术前放疗与手术前未放疗的随机对照研究结果。其目的是研究术前放疗能否降低盆腔复发率以及局部复发率降低能否延长患者的生存率。中位随访时间53个月(8～90个月)术前放疗组424例,术前未放疗组425例,两组共行直肠癌根除性切除679例。849例病人在术前都行活检证实为直肠腺癌。侧位 X线显示癌瘤上端在骶骨岬水平以下,无远处扩散,临床认
This article reports the results of a randomized controlled study of preoperative radiotherapy and preoperative radiotherapy for 849 patients with resectable rectal cancer from 13 institutions in the rectal cancer research group in Stockholm. Its purpose is to investigate whether preoperative radiotherapy can reduce the rate of pelvic recurrence and whether the decrease in local recurrence rate can prolong survival. The median follow-up time was 53 months (8 to 90 months) in 424 preoperative radiotherapy groups and 425 in the unadjuvant preoperative radiotherapy group. Two groups underwent radical resection of 679 rectal cancers. 849 patients were biopsied and confirmed as rectal adenocarcinoma before surgery. Lateral X-rays show that the upper end of the tumor is below the level of the sacrum, with no distant proliferation.