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目的：用彩色多普勒血流成像（ｃｏｌｏｒｄｏｐｐｌｅｒｆｌｏｗｉｍａｇｉｎｇ，ＣＤＦＩ）技术研究青光眼病人眼血流动力学变化及检测指标的可靠性。方法：采用美国Ａｃｕｓｏｎ－１２８ＸＰ型彩色多普勒超声仪测量原发性开角型青光眼（ｐｒｉｍａｒｙｏｐｅｎ－ａｎｇｌｅｇｌａｕｃｏｍａ，ＰＯＡＧ）２５例，原发性闭角型青光眼（ｐｒｉｍａｒｙａｎｇｌｅ－ｃｌｏｓｅｇｌａｕｃｏｍａ，ＰＡＣＧ）３０例和正常人３０例的眼动脉（ｏｐｈｔｈａｌｍｉｃａｒｔｅｒｙ，ＯＡ）、视网膜中央动脉（ｃｅｎｔｒａｌｒｅｔｉｎａｌａｒｔｅｒｙ，ＣＲＡ）、后短睫状动脉（ｓｈｏｒｔｐｏｓｔｅｒｉｏｒｃｉｌｉａｒｙａｒｔｅｒｙ，ＳＰＣＡ）的血流动力学指标。同期测量眼压、血压。结果：①正常组内除年龄大者ＣＲＡ的搏动指数（ｐｕｌｓａｔｉｌｉｔｙｉｎｄｅｘ，ＰＩ）较高外，其他各血管血流动力学指标在性别、眼别间无显著差异（Ｐ＞０．０５）。②ＰＯＡＧ组血流动力学指标异常。主要表现为ＣＲＡ、ＳＰＣＡ血管阻力增高（Ｐ＜０．０１），且在视野改变中期明显。③血流动力学指标中阻力指数（ｒｅｓｉｓｔｉｖｅｉｎｄｅｘ，ＲＩ）变异最小、最稳定。结论：局部血液循环障碍在ＰＯＡＧ发病中起?
OBJECTIVE: To study the ocular hemodynamic changes and the reliability of the detection parameters in patients with glaucoma by color Doppler flow imaging (CDFI). Methods: 25 cases of primary open angle glaucoma (POAG), 30 primary angle-closeglaucoma (PACG) and 30 normal primary angle-angle glaucoma (PACG) were measured by American Acuson-128XP color Doppler. The hemodynamics of ophthalmicartery (OA), central retinalartery (CRA) and short posterior ciliary artery (SPCA) in 30 patients were analyzed. Simultaneous measurement of intraocular pressure, blood pressure. Results: ① In the normal group, except CRA with higher age, pulsatility index (PI) was higher, but there was no significant difference in hemodynamics among the other groups (P> 0.05). ② POAG hemodynamic abnormalities. The main manifestations of CRA, SPCA vascular resistance increased (P <0.01), and mid-term visual field changes significantly. ③ The index of resistance (resistive index) in hemodynamics is the smallest and the most stable. Conclusion: Local blood circulation disorder plays a role in the pathogenesis of POAG?