论文部分内容阅读
目的对采用抑酸维持治疗女性更年期糖尿病合并消化性溃疡患者的获益进行分析。方法收集更年期女性糖尿病合并消化性溃疡100例,随机分为观察1组50例,对照1组50例;选择同期治疗更年期女性单纯糖尿病患者80例,随机分成观察2组40例,对照2组40例。观察四组患者的临床疗效。结果四组间幽门螺杆菌根除与溃疡愈合例数相当,差异无统计学意义(P>0.05);糖尿病合并溃疡两组与单纯糖尿病两组间在使用常规治疗与抑酸治疗的1年内分别复发7例、33例、19例和3例,复发率为14.0%、66.0%、47.5%和7.5%,与对照1组比,观察1组、对照2组和观察2组的复发率比较低(P<0.05);与对照2组比,观察1、2组复发率较低(P<0.05),四组治疗前后比较差异具有统计学意义(P<0.05)。结论更年期糖尿病合并消化性溃疡与单纯糖尿病之间的症状存在差异,可使用抑酸治疗。
OBJECTIVE: To analyze the benefits of acid suppression in the treatment of menopausal diabetic patients with peptic ulcer. Methods 100 cases of menopausal women with diabetes mellitus and peptic ulcer were collected and randomly divided into observation group (50 cases) and control group (50 cases). 80 cases of menopausal women with simple diabetes mellitus were randomly divided into observation group (40 cases) and control group (40 cases) example. To observe the clinical efficacy of four groups of patients. Results There was no significant difference between the four groups in the number of cases of H. pylori eradication and ulcer healing (P> 0.05). The two groups with diabetes mellitus and ulcer were relapsed within one year of routine treatment and acid suppression treatment respectively The recurrence rates were 14.0%, 66.0%, 47.5% and 7.5% in 7 cases, 33 cases, 19 cases and 3 cases, respectively. Compared with control group 1, the recurrence rates of observation group 1, control group 2 and observation group 2 were lower P <0.05). Compared with the control group 2, the recurrence rate in the observation group 1,2 was lower (P <0.05). There was significant difference between the four groups before and after treatment (P <0.05). Conclusions There are differences in the symptoms of menopause between diabetic peptic ulcer and simple diabetes mellitus, and acid suppression can be used.