论文部分内容阅读
目的:探讨脉压(PP)与冠状动脉病变(CAD)程度的关系。方法:对515例因胸痛而住院的患者进行冠状动脉造影,分析确诊的338例冠心病患者和177例非冠心病患者的年龄、收缩压(SBP)、舒张压(DBP)、平均压(MAP)、PP和CAD支数等临床特点。结果:①与非冠心病患者相比,冠心病患者的年龄、SBP、MAP和PP均增加,男性和并发高血压病(EH)比例均增加(P<0.05,P<0.01)。②随着CAD支数的逐渐增加,年龄增加的变化,以及男性和并发EH比例增加的变化均有高度显著性差异(均P<0.01);SBP和PP增加的变化有显著性差异(均P<0.05)。与非冠心病患者相比,1支病变、2支病变和3支病变患者的年龄、SBP、MAP和PP增加,男性和并发EH比例均增加(P<0.05,P<0.01);3支病变与1支病变相比年龄增加(P<0.05)。③随着PP的逐渐增加,冠心病患者的年龄、SBP、MAP和CAD支数均逐渐增加,并发EH比例亦逐渐增加,均有高度显著性差异(均P<0.01);男性比例呈减低改变,有高度显著性差异(P<0.01)。结论:PP水平与CAD有显著的关系:PP增大者,其CAD支数增加;而PP的增加与年龄和并发EH的增加有关。
Objective: To investigate the relationship between pulse pressure (PP) and coronary artery disease (CAD). Methods: A total of 515 patients hospitalized with chest pain undergoing coronary angiography were enrolled. The age, SBP, DBP and MAP of 338 patients with CHD and 177 patients with CHD were analyzed. ), PP and CAD count and other clinical features. Results: ①The age, SBP, MAP and PP of coronary heart disease patients were increased compared with those of non-coronary heart disease patients, and the proportions of male and concurrent hypertension (EH) were increased (P <0.05, P <0.01). (2) With the increase of CAD count, the change of age and the increase of male and concurrent EH had highly significant difference (all P <0.01); the changes of SBP and PP increased significantly (P <0.05). Compared with non-CHD patients, the age, SBP, MAP and PP of 1-vessel, 2-vessel and 3 vessel lesions increased, while the proportion of male and concurrent EH increased (P <0.05, P <0.01) Compared with 1 disease increased age (P <0.05). ③ With the gradual increase of PP, the age, SBP, MAP and CAD count of CAD patients increased gradually, and the proportion of complicated EH also increased gradually. There was a highly significant difference (all P <0.01) , There is a highly significant difference (P <0.01). Conclusion: There is a significant relationship between PP level and CAD: when PP is increased, the CAD count increases; while the increase of PP is related to the increase of age and concurrent EH.