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目的术后随访观察术前行长疗程放疗的中低位直肠癌患者。方法中低位直肠癌患者47例术前行长疗程放疗,时间30-40d,治疗22-26次,总剂量为45.0-46.2Gy,随访观察患者5、10、12年总生存率、无瘤生存率、局部复发率。结果 47例患者保肛率为80.9%(38/47),5、10、12年总生存率分别为72.3%、52.0%、49.4%,无瘤生存率分别为66.0%、51.7%、45.7%,局部复发率分别为7.6%、14.6%、14.6%。结论中低位直肠癌患者术前行长疗程放疗,提高了保肛率及总生存率,改善了生活质量。
Objective To observe the postoperative patients with preoperative long course of radiotherapy in patients with low rectal cancer. Methods 47 patients with low rectal cancer underwent preoperative long course radiotherapy for 30-40 days for 22-26 times with a total dose of 45.0-46.2 Gy. The patients were followed up for a total of 5, 10 and 12 years of total survival and tumor-free survival Rate, local recurrence rate. Results The survival rate of the anus in 47 patients was 80.9% (38/47). The overall survival rates at 5, 10 and 12 years were 72.3%, 52.0% and 49.4% respectively. The tumor-free survival rates were 66.0%, 51.7% and 45.7% The local recurrence rates were 7.6%, 14.6% and 14.6% respectively. Conclusion The preoperative grenade course radiotherapy in patients with low or middle rectal cancer improves the rate of anus retention and overall survival, and improves the quality of life.