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随着细而柔韧的光导纤维的发展,激光在心血管疾病治疗中的应用有其前途。本文是在兔的动脉粥样硬化模型中,研究激光辐照的急性和慢性血管反应。方法:7只重为2.8～5公斤的白兔,喂以含有2％胆固醇的兔饲料3～5个月,造成主动脉粥样硬化。5只兔行正中胸骨切开术。切除心包,找到左心室尖,通过荷包口缝合插入小的导管内针,把短导管穿入左心室腔并移去内针。通过导管插入一直径为400微米柔韧的石英芯线纤维,其顶端置在升主动脉粥样硬化处,另一端连于氩激光源。2只兔经腹部正中切口分离腹主动脉分叉下的髂动脉,把直径为
With the development of thin and flexible optical fibers, the application of laser in the treatment of cardiovascular diseases has its future. This article examines acute and chronic laser-induced vascular responses in the rabbit model of atherosclerosis. Methods: Seven rabbits weighing 2.8 to 5 kg were fed 3 to 5 months of diet with 2% cholesterol, resulting in aortic atherosclerosis. 5 rabbits underwent sternotomy. The pericardium is removed, the tip of the left ventricle is found, a small catheter needle is inserted through the sack mouth, the short catheter is inserted into the left ventricular cavity and the inner needle is removed. A 400 micron diameter flexible quartz core fiber was inserted through the catheter, with the top of the ascending aortic atherosclerosis and the other end attached to an argon laser source. 2 rabbits were separated by a median incision of the abdominal aorta iliac artery bifurcation, the diameter of