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目的了解腹泻婴幼儿轮状病毒(RV)感染情况并探讨其发病特点,为临床诊治提供依据。方法采用胶体金法检测就诊的腹泻婴幼儿粪便标本RV,并对结果进行分析。结果 8 998例腹泻婴幼儿,粪便标本RV阳性2 873例,阳性率为31.93%;2010和2011年10～12月份阳性率最高,分别为35.85%和41.65%,1～3月份阳性率分别为32.54%和35.11%;1～2岁患儿RV阳性率最高,达36.85%;男童与女童RV阳性率分别为32.67%和30.98%,差异无统计学意义(P>0.05);2 873例阳性标本中脂肪球阳性37.28%。结论 1～2岁婴幼儿是RV感染的高危人群;RV感染有明显季节性,高发于每年的10月到次年3月。
Objective To understand the status of rotavirus (RV) infection in infants and young children and explore the characteristics of the pathogenesis in order to provide the basis for clinical diagnosis and treatment. Methods Colloidal gold method was used to detect the RV of diarrhea infants and young children attending the clinic, and the results were analyzed. Results 8 898 cases of diarrhea in infants and young children, stool specimens RV positive 2 873 cases, the positive rate was 31.93%; 2010 and 2011 10 to December the highest positive rates were 35.85% and 41.65%, 1 to March were respectively 32.54% and 35.11%, respectively. The positive rate of RV was the highest in children aged 1-2 years (36.85%). The positive rates of RV in boys and girls were 32.67% and 30.98% respectively, with no significant difference (P> 0.05) Positive samples of fat globules were 37.28% positive. Conclusions Infants aged 1-2 years old are at high risk of RV infection. RV infection is obviously seasonal and occurs frequently from October to next March.