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目的 :观察四黄调胃汤、PPI三联疗法及两者联合疗法对脾气虚兼湿热气滞型幽门螺杆菌 (Hp)相关性胃炎及消化性溃疡的疗效。方法 :3种不同疗法分别治疗脾气虚兼湿热气滞型 Hp相关性胃炎及消化性溃疡的患者 ,观察中医症候总积分、消化性溃疡和慢性胃炎疗效、Hp根除率及综合疗效等。结果 :四黄调胃汤与 PPI三联疗法联合能够改善消化性溃疡的临床症状 ,提高溃疡的愈合率 ;Hp根除率比单纯四黄调胃汤和单纯 PPI三联疗法均有提高 ;3种疗法对胃炎治疗效果均非常明显 ;四黄调胃汤与 PPI疗法联合及单纯四黄调胃汤改善临床症状效果优于单纯 PPI三联 ;四黄调胃汤与 PPI三联疗法联合 ,对 Hp相关性胃炎及消化性溃疡的总有效率明显高于单纯四黄调胃汤和单纯 PPI三联疗法。结论 :四黄调胃汤及 PPI三联结合其综合疗效明显高于单纯中药或西药。
Objective: To observe the curative effect of Sihuang Tiawei Soup, PPI triple therapy and combination therapy on gastritis associated with Helicobacter pylori (Hp) -related gastritis and peptic ulcer due to spleen deficiency and damp-heat syndrome. Methods: Three kinds of different therapies were used to treat patients with Hp-related gastritis and peptic ulcer with spleen-qi deficiency and dampness-heat stagnation, and to observe the total symptom score of TCM, the curative effect of peptic ulcer and chronic gastritis, the eradication rate of Hp and the comprehensive curative effect. Results: The combination of Sihuang Tiawei Soup with PPI triple therapy could improve the clinical symptoms of peptic ulcer and improve the healing rate of ulcer. Hp eradication rate was higher than that of Sihuang Tiawei Soup and simple PPI triple therapy. Gastritis treatment effect is very obvious; Sihuang Tiawei soup combined with PPI therapy and Sihuan Tweezers alone improve the clinical symptoms better than pure PPI triple; Sihuang Tiawei soup and PPI triple therapy, Hp-related gastritis and The total effective rate of peptic ulcer was significantly higher than pure Sihuangwei stomach soup and simple PPI triple therapy. Conclusion: The comprehensive curative effect of Sihuangwei Wei Tang and PPI triple therapy is obviously higher than simple Chinese medicine or Western medicine.