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对20例松果体区肿瘤患者进γ-刀治疗。肿瘤三维平均直径在12~37mm严均22mm)。术前Karnofsky评分为30%~70%(平均50%)。等中心照射点1~10个(平均3.8个),肿瘤边缘等剂量曲线为30%~70%(平均50%),剂量为9.9~20Gy(平均14.3Gy)。肿瘤最大中心剂量为22~50Gy(平均35Gy)。结果:治疗过程顺利,未出现仲何近期并发症。术后随访10例,平均随访时间2.6月,CT或MRI检查示:病灶缩小4例,不变4例,增大2例。随访时Karnofsky评分为30%~90%(平均80%)。初步临床显示,γ-刀对松果体区肿瘤的治疗是简便、安全的,对控制肿瘤生长有明显作用。并对γ-刀在治疗松果体区肿瘤中的问题进行讨论。
20 cases of pineal region tumor patients into γ-knife treatment. Tumor three-dimensional average diameter of 12 ~ 37mm strict average 22mm). Preoperative Karnofsky score was 30% to 70% (average 50%). The isocenter ranged from 1 to 10 sites (mean, 3.8). The isodose curves at the margins of the tumor ranged from 30% to 70% (average 50%) with a dose of 9.9-20 Gy (average 14.3 Gy). The largest tumor center dose of 22 ~ 50Gy (average 35Gy). Results: The course of treatment was smooth and there was no recent secondary complications. All cases were followed up for 10 cases. The average follow-up time was 2.6 months. CT or MRI showed that the lesion was reduced in 4 cases, unchanged in 4 cases and increased in 2 cases. Karnofsky score at follow-up ranged from 30% to 90% (average, 80%). Preliminary clinical evidence shows that γ-knife treatment of pineal region tumors is simple and safe and has a significant effect on the control of tumor growth. And the γ-knife in the treatment of pineal tumor in the area to be discussed.