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作者对1979年11月～1982年4月期间瑞士洛桑和伯尔尼大学儿童医院的51例细菌性脑膜炎并发耳聋情况进行了研究。病儿中男27,女24;年龄1周～16岁,58.8%小于3岁。治疗用药为羟氨苄青霉素、氯霉素、青霉素、头孢氨呋肟(cefuroxime)等,未用激素。确诊脑膜炎后,便尽早用脑干诱发电位(BAEP)法测听,首次测试常在确诊后48小时。若首次试测正常,则在出院前复测,但如在住院期间发现可疑耳聋,则每周复查一次,直至出院;若首次测听异常,则至少每周复测一次,直至出院,并再追踪3个月。结果可分为三种情况:1组35例(68.6%),听力一直正常;2组11例(21.6%)曾有一过性耳聋;3组5例(9.8%)呈持久性聋,出院后3个月并经行为测听核实。据分析,病儿耳聋的发生与否无性别差异,与治疗开始的迟早无统计学关联,与脑
The authors studied 51 cases of bacterial meningitis complicated with deafness at the Children’s Hospital of Lausanne, Switzerland, and Bern University from November 1979 to April 1982. The sick child male 27, female 24; age 1 week ~ 16 years old, 58.8% less than 3 years old. Drugs for the treatment of amoxicillin, chloramphenicol, penicillin, cefuroxime (cefuroxime), without the use of hormones. After diagnosis of meningitis, as soon as possible with brainstem evoked potentials (BAEP) audiometry, the first test often 48 hours after diagnosis. If the test is normal for the first time, it will be retested before discharge. However, if suspicious deafness is found during the hospitalization, it will be reviewed once a week until discharge. If the abnormality is detected for the first time, retest at least once a week until discharge and Track 3 months. The results were divided into three groups: 35 cases (68.6%) in group 1 had normal hearing; 11 cases (21.6%) had transient deafness in group 2; and 5 cases (9.8% 3 months and verified by the audition. According to the analysis, the incidence of deafness in children with or without gender differences, and treatment of the early and no significant correlation between brain and brain