板蓝根制剂有效成分分析

来源 :南京中医学院学报 | 被引量 : 0次 | 上传用户:yifengwuyang
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板蓝根制剂(冲剂、干糖浆)在临床上应用很广泛,具有清热、解毒、凉血的作用,主要用于治疗流行性感冒、防治流行性乙型脑炎和流行性腮腺炎、治疗传染性肝炎、暴发性红眼、单纯性疱疹性口炎、及治疗扁平疣等。据文献报道,板蓝根中的主要有效成份为靛玉红。靛玉红具有抗白血病作用,对治疗慢性粒细胞白血病有显著疗效,还具有抗肿瘤作用。我们对15个厂家所生产的21批板蓝根制剂中的靛玉红和几种氨基酸用薄层扫描法进行了定量分析,并用氯气敏电极法测定了总氮量(因为其中的主要成分均为含氮化合物)。报道如下。 Radix isatidis preparations (granules, dry syrup) are widely used in clinical practice and have functions of heat-clearing, detoxification and cooling. They are mainly used to treat influenza, prevent Japanese encephalitis and epidemic parotitis, and treat infectious hepatitis. , fulminant red eyes, herpes simplex, and flat warts. According to reports in the literature, the main active ingredient in Isatis indigotica is Indirubin. Indirubin has an anti-leukemia effect and is effective in the treatment of chronic myelogenous leukemia. It also has an anti-tumor effect. We quantified indirubin and several amino acids in 15 batches of Radix isatidis, which were produced by 15 manufacturers, and determined the total nitrogen using the chlorine gas sensitive electrode method (because the main components are Nitrogen compounds). The report is as follows.
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