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用p53、p21通过免疫组织化学技术SP法和用真彩色图像分析系统对30例粘波表皮样癌进行检测和DNA含量分析,结果表明组织分化程度愈差的p53、p21表达增强且DNA含量亦增高.提示:粘波表皮样癌的DNA含量与p53、p21表达量可能存在一致性关系.两者对判断肿瘤的恶性程度、评估预后有一定的意义.
Using p53, p21 by immunohistochemistry SP method and using true color image analysis system for 30 cases of sticky epidermoid carcinoma and DNA content analysis, the results showed that the poorer degree of differentiation of p53, p21 expression was enhanced and the DNA content was also Increased. Tip: There may be a consistent relationship between DNA content and the expression of p53 and p21 in the epidermoid carcinoma. Both have a certain significance for judging the degree of malignancy and evaluating prognosis.