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采用体内、外试验，对替硝唑和甲硝唑阴道泡腾片抗阴道毛滴虫作用进行了比较研究。结果体外试验表明：替硝唑阴道泡腾片的最小抑虫浓度为２５μｇ／ｍｌ，而甲硝唑阴道泡腾片的最小抑虫浓度为５０μｇ／ｍｌ，最小杀虫浓度为１００μｇ／ｍｌ。体内试验表明：替硝唑阴道泡腾片低、高两个剂量组和甲硝唑阴道泡腾片治疗组的疗效一致，所有动物均被治愈，空白对照组无疗效。说明替硝唑阴道泡腾片和甲硝唑阴道泡腾片均有良好的抗滴虫疗效，且前者疗效更佳
The effects of tinidazole and metronidazole vaginal effervescent tablets against Trichomonas vaginalis were compared in vitro and in vivo. Results The in vitro test showed that the minimum inhibitory concentration of tinidazole vaginal effervescent tablets was 25μg / ml, while the minimum inhibitory concentration of metronidazole vaginal effervescent tablets was 50μg / ml and the minimum pesticidal concentration was 100μg / ml. In vivo tests showed that the efficacy of tinidazole vaginal effervescent tablets in both low and high dosage groups and metronidazole vaginal effervescent tablets treatment group were the same, all animals were cured, and the blank control group had no effect. Tinidazole vaginal effervescent tablets and metronidazole vaginal effervescent tablets have good anti-trichomonad effect, and the former is more effective