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1目的 探讨血清铁蛋白 (SF)与 2型糖尿病病人糖代谢和胰岛素抵抗的关系。 2方法 采用放免法测定 96例 2型糖尿病病人及 32例正常人的 SF和胰岛素水平 ,并同时检测血糖、血脂等。3结果 2型糖尿病病人血清 SF明显高于正常人 (t=4.2 2 ,P<0 .0 0 1)。 SF水平与血糖、糖尿病慢性并发症及胰岛素抵抗有关 (F=6 7.36 ,72 .82 ,q=6 .2 4～ 9.32 ,P均 <0 .0 1;t=3.2 40 ,P<0 .0 1)。 4结论 血清 SF变化对 2型糖尿病病人的糖代谢及胰岛素抵抗有影响作用
1 Objective To investigate the relationship between serum ferritin (SF) and glucose metabolism and insulin resistance in type 2 diabetic patients. 2 method of radioimmunoassay 96 cases of type 2 diabetic patients and 32 normal subjects SF and insulin levels, and simultaneous detection of blood glucose, blood lipids and so on. 3 Results Type 2 diabetes patients with serum SF was significantly higher than normal (t = 4.2 2, P <0.001). The levels of SF were related to the blood glucose, chronic complications of diabetes and insulin resistance (F = 6 7.36, 72.82, q = 6.24 ~ 9.32, P <0.01; t = 3.240, P < 1). 4 Conclusion Serum SF changes in patients with type 2 diabetes, glucose metabolism and insulin resistance effect