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目的:为进一步探索肾综合征出血热(HFRS)流行规律与疫源地类型,以制定防制对策。方法:采用直接免疫荧光法(FAT)检测鼠肺汉坦病毒(HV)抗原;采用间接免疫荧光法(IFAT)检测EHF病人血清中抗体,血凝抑制试验(HI)进行血清学分型。结果:全省2230例病人,主要分布在浙东和浙西丘陵区,全年均有病例发生,1月和5、6、7月为二个发病高峰,病例主要发生在青壮年农民。结论:对以姬鼠型为主的混合型疫区,血选择双价疫苗进行预防接种,以控制疫情。
Objective: To further explore the epidemic of hemorrhagic fever with renal syndrome (HFRS) and the types of foci in order to formulate control strategies. Methods: Hantavirus (HV) antigen of mouse lung was detected by direct immunofluorescence (FAT); Serum antibody and hemagglutination inhibition (HI) were detected by indirect immunofluorescence assay (IFAT). Results: 2230 patients in the province were mainly distributed in the hilly areas of eastern Zhejiang and western Zhejiang. Cases occurred in all the year, and in January and May, June and July, two peak incidence occurred. The cases mainly occurred in young and middle-aged peasants. Conclusion: In order to control the epidemic situation, vaccination should be carried out on the mixed type epidemic area which is mainly based on the Apodemus type and the blood type.