目的探讨甲状旁腺99mTc-MIBI核素显像联合甲状旁腺彩超对甲状旁腺腺瘤误诊原因,以期提高对本病的认识及早期诊断水平。方法通过对1例术前甲状旁腺99mTc-MIBI核素显像及甲状旁腺彩超误诊甲状旁腺腺瘤诊治经过的回顾性分析,结合有关文献,探讨原发性甲状旁腺功能亢进、甲状旁腺腺瘤的误诊原因和诊断思路。结果术前甲状旁腺99mTcMIBI核素显像联合甲状旁腺彩超诊断为甲状旁腺腺瘤的病灶术后病理结果证实为“结节性甲状腺肿”。结论临床医师诊治经验不足、思维局限、对原发性甲旁亢的临床表现及各项生化检查缺乏了解,一味的相信甲状旁腺99mTc-MIBI核素显像及甲状旁腺彩超的检查结果是导致本例误诊的主要原因。提示临床医师应开阔诊断思路,全面分析问题,结合患者各项临床表现及各项实验室检查深入询问,合理选择医技检查,以避免误诊误治的发生。 Objective To investigate the causes of misdiagnosis of parathyroid gland hyperplasia by parathyroid 99mTc-MIBI combined with parathyroid gland radiography in order to improve the understanding and early diagnosis of this disease. Methods A retrospective analysis of 99mTc-MIBI radionuclide imaging and parathyroid color Doppler imaging of parathyroid adenoma before surgery was performed. One hundred patients with primary hyperparathyroidism, thyroid hyperplasia, Misdiagnosis and diagnosis of parathyroid adenoma. Results Preoperative parathyroid 99mTcMIBI nuclide imaging combined with parathyroid ultrasound diagnosis of parathyroid adenoma lesions pathological results confirmed as “nodular goiter.” Conclusions Clinicians lack of experience in diagnosis and treatment, limited thinking, the clinical manifestations of primary hyperparathyroidism and lack of understanding of the biochemical examination, blindly believe that parathyroid 99mTc-MIBI radionuclide imaging and parathyroid ultrasound examination results are Lead to misdiagnosis in this case the main reason. Tip clinicians should broaden the diagnostic ideas, a comprehensive analysis of the problem, combined with the patient’s clinical manifestations and laboratory tests in-depth inquiry, a reasonable choice of medical examination to avoid misdiagnosis and mistreatment.