论文部分内容阅读
目的:分析胺碘酮静脉给药过程中发生休克的一般规律,为临床合理用药提供参考方法:检索中文期刊全文库、万方数据库及我院药品不良反应报告数据库,收集2003～2011年关于胺碘酮静脉给药所引起患者休克的文章期刊和个案报道,对患者的基础心脏病、心律、血压、心功能状态、心电图和胺碘酮的用法用量及胺碘酮的溶酶、注射速度、浓度、和休克发生的时间、休克表现及抢救措施等项目进行统计分析结果:共收集15例因静脉给药胺碘酮所引起的休克的患者临床病例,其中3例是我院住院的患者。用药后休克发生的时8例≤3 min,7例≤20 min,休克持续时间为2～360 min。12例停药并给予抢救药物治疗3例仅停给予吸氧,未使用药物治疗。结论:胺碘酮静脉给药可能引起休克,及时对症治疗可缓解
OBJECTIVE: To analyze the general rules of shock during intravenous administration of amiodarone and to provide a reference method for clinical rational drug use: To search the full-text database of Chinese periodicals, Wanfang database and ADR database of our hospital, Idiopathic patients caused by shock intravenous journals and case reports of patients with basic heart disease, heart rate, blood pressure, cardiac function, electrocardiogram and amiodarone usage and dosage of amiodarone, the injection rate, Concentration, and the time of shock, shock performance and rescue measures and other projects were analyzed: a total of 15 cases of patients with intraventricular administration of amiodarone-induced shock clinical cases, of which 3 cases were hospitalized patients. 8 cases of shock occurred after treatment ≤ 3 min, 7 cases ≤ 20 min, shock duration of 2 ~ 360 min. 12 patients stopped and given rescue medication 3 patients were given only oxygen, without medication. Conclusion: Amiodarone intravenous administration may cause shock, symptomatic treatment can be alleviated in time