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目的研究Tei指数在母体不同孕期、不同血糖控制水平下妊娠期糖尿病(GDM)胎儿心功能测定中的价值。方法选取我院2014年1月~2015年10月GDM孕妇血糖控制不良者44例、GDM孕妇血糖可控者42例及正常妊娠孕妇43例作为研究对象。每位孕妇分别于孕24~28周、孕~33周、孕~38周、孕>38周及以上的时段内进行超声心动图检查,利用脉冲多普勒及组织多普勒测量计算左右心室的射血分数及Tei指数,分析不同孕周3组研究对象射血分数及Tei指数的变化规律。结果正常组、可控组、控制不良组胎儿之间左、右心室射血分数无明显差异。正常组胎儿左、右心室Tei指数随孕周的增加而逐渐降低。可控组胎儿左、右心室Tei指数随孕周增加而逐渐升高,且在34~38周上升较快。控制不良组胎儿左、右心室Tei指数也随孕周增加而逐渐升高,且在29~33周上升较快。结论 Tei指数可作为评价妊娠期糖尿病胎儿心功能的可靠指标。
Objective To study the value of Tei index in the determination of fetal cardiac function in gestational diabetes mellitus (GDM) under different blood glucose levels in different pregnant mothers. Methods Forty-four patients with poorly controlled glycemic control of GDM in our hospital from January 2014 to October 2015 were selected. Forty-two patients with GDM and 42 normal pregnant women were selected as study subjects. Each pregnant woman was examined by echocardiography within 24-28 weeks of pregnancy, 33 weeks of pregnancy, 38 weeks of pregnancy, 38 weeks of pregnancy and above, and the left and right ventricles were calculated by pulsed Doppler and tissue Doppler The ejection fraction and the Tei index were calculated. The changes of ejection fraction and Tei index of the three groups were analyzed. Results There was no significant difference in left and right ventricular ejection fraction between normal control group, controllable group and control poor group. Tei index of left ventricle and right ventricle in normal group decreased gradually with the increase of gestational age. Control group left and right fetal heart Tei index gradually increased with gestational weeks increased, and in 34 to 38 weeks increased rapidly. Tei index of right and left ventricles of fetuses with poor control group also increased gradually with the increase of gestational weeks, and rose rapidly from 29 to 33 weeks. Conclusion Tei index can be used as a reliable indicator of fetal cardiac function in gestational diabetes mellitus.