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糖尿病周围神经病变55例,其中30例(男性19例,女性11例;年龄52±s 8a)采用藻酸双酯钠(PSS)0.1g, tid, po,共治疗90d。另25例(男性16例,女性9例;年龄53±8a)采用维生素B_1和(或)阿司匹林常规剂量口服为常规组,疗程同上。结果:PSS组起效快(3-10d),症状及浅感觉的改善非常显著,肌腱反射较慢,总有效率为97％。常规组起效慢(>10d),而症状、浅感觉及肌腱反射改善均较慢,总有效率为80％,2组差别有显著意义(P<0.05)。
Thirty-five diabetic patients with peripheral neuropathy (30 males and 19 females and 11 females; age 52 ± s8a) were treated with PSS 0.1g, tid, po for 90 days. The other 25 cases (16 males and 9 females; age 53 ± 8a) were treated with the conventional dose of vitamin B_1 and / or aspirin, and the treatment was the same as above. Results: The onset of onset of PSS was fast (3-10 days). The improvement of symptoms and superficial sensation was very significant. The tendon reflex was slow and the total effective rate was 97%. The routine group had a slow onset (> 10 days), while the symptoms, superficial feeling and tendon reflexes were slowed down. The total effective rate was 80%. There was significant difference between the two groups (P <0.05).