糖链抗原CA_(50)与1983年问世以来各国学者对它的基础和临床进行了大量研究,对肿瘤临床工作发挥了一定的有意义作用,笔者复习了大量有关文献综述如下.1 CA_(50)的概况CA_(50)(Cabohydrate Antigen 50)是1983年瑞典学者Lindholm等人首先发现并报道的.他们用人结肠癌细胞培养的细胞株(Colo-205)免疫小鼠,得到免疫的脾细胞,再与小鼠的骨髓瘤细胞杂交,得到一系列单克隆 The sugar chain antigen CA_(50) has been extensively studied by scholars from various countries since its inception in 1983. It has played a significant role in the clinical work of tumors. The author reviewed a large number of relevant literatures as follows.1 CA_(50) The overview of CA 50 (Cabohydrate Antigen 50) was first discovered and reported by Swedish scholar Lindholm et al. in 1983. They immunized mice with human colon cancer cell-cultured cell line (Colo-205) and obtained immunized spleen cells. Then hybridize with mouse myeloma cells to obtain a series of monoclonal