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目的:观察决明子散剂的调脂疗效及安全性。方法:将114例高脂血症患者,随机分为2组,第1组57例,服决明子散剂,4g/次,bid.。第2组57例,服安慰剂胶囊,1粒/次,bid。疗程均为8周。结果:与服药前相比,8周后,决明子散剂组平均血清TC、LDLC、TG水平和TC/HDLC比值分别下降12.7%、10.1%、34.7%、及15.9%,HDLC升高11.7%(P<0.05~0.001)。降低幅度均明显大于安慰剂组(P均<0.001)。未见有临床意义的副作用。结论:决明子散剂是一种安全、有效及易耐受的血脂调节药。
Objective: To observe the efficacy and safety of Cassia seed powder in regulating lipid regulation. Methods: 114 cases of hyperlipidemia patients were randomly divided into two groups, the first group of 57 cases, taking Dingdingzi powder, 4g / time, bid. . Group 2 57 cases, placebo capsules, 1 / time, bid. The course of treatment is 8 weeks. Results: After 8 weeks, the serum levels of TC, LDLC, TG and TC / HDLC in the Cassiaei powder group decreased by 12.7%, 10.1% and 34.7% respectively, and 15.9%, HDL C increased by 11.7% (P <0.05 ~ 0.001). The reduction was significantly greater than placebo (P <0.001). No clinically significant side effects. Conclusion: Cassia powder is a safe, effective and easy to tolerate blood lipid regulating drugs.