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The present manuscript describes solid-state synthesis of some reported steroidal pyrazolines by a novel eco-friendly route.The synthesized pyrazolines were compared with those obtained from conventional methods in terms of reaction time and overall yield. A substantial enhancement in reaction rate and yield was observed.The antimicrobial activity and the subsequent molecular docking studies of the steroidal pyrazolines have also been carried out.
The present manuscript describes solid-state synthesis of some reported steroidal pyrazolines by a novel eco-friendly route. The synthesized pyrazolines were compared with those obtained from conventional methods in terms of reaction time and overall yield. A substantial enhancement in reaction rate and yield was observed. The antimicrobial activity and the subsequent molecular docking studies of the steroidal pyrazolines have also been carried out.