李××,男,24岁,军官。患者因手部感染,于10月10日早6时来门诊。开始用青霉素水剂治疗。未治疗之先,用1:2000单位青霉素作前臂皮内过敏试验。30分钟后观察无反应,才确定每6小时肌注10万单位。注射后6小时病人无任何不适。至当天中午12时第二次注射后,病人自觉心窝部不适、疼痛、足底发痒。可是,病人未将此种情况告诉医护人员,故继续注射。10月11日上午病人又觉咽部不适,心窝部疼痛加剧(患者无胃痛史),不思饮食,恶心感。服用(?)茄合剂治疗无效。当天下午全身出现荨麻疹。体检:除患者表情烦恼,咽部潮红、水肿,及全身成片状突山之皮疹外,其他未见异常。化验检查:白血球总数8,750,中性71%,淋巴28%,酸性1%。故使我们想到为青霉素迟发过敏性反应,立即停用青霉素(共注射了60万单位),给予苯海拉明、维生素丙口服;静脉注射氯化 Lee × ×, male, 24 years old, officer. Patients with hand infections, as early as October 10 at the clinic. Begin treatment with penicillin. Before treatment, 1: 2000 penicillin for forearm intradermal allergy test. Observed no reaction after 30 minutes, only to determine every 6 hours intramuscularly 100,000 units. Six hours after injection the patient did not have any discomfort. To the day after the second injection at 12 noon, the patient consciously felt uncomfortable in the wobar, pain, and itchy feet. However, the patient did not tell the medical staff this situation, so continue injection. On the morning of October 11, the patient again feels throat discomfort, aggravating pain in the heart and socket area (the patient has no history of stomach pain), does not think of diet and nausea. Taking (?) Soap mixture therapy is invalid. Hives appeared throughout the afternoon. Physical examination: In addition to the patient’s facial expressions, throat flushing, edema, and the whole body into a patchy mountain rash, the other without exception. Laboratory tests: the total number of white blood cells 8,750, 71% neutral, lymphatic 28%, 1% acidic. Therefore, we think of delayed allergic reactions to penicillin, immediate withdrawal of penicillin (600,000 units were injected), given diphenhydramine, vitamin C oral; intravenous chlorination