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目的 探讨动脉化疗对晚期胰腺癌的治疗作用。方法 78例晚期胰腺癌 ,经股动脉穿刺、选择性动脉插管 ,灌注 5 -Fu、表阿霉素、顺铂 ,间歇 1～ 3个月 ,灌 2～ 8次。有黄疸者手术行胆道内引流术 ,其中植入化疗泵 12例。结果 生存期 3～ 3 6个月 ,中位生存期 9.8个月 ,瘤体大部分缩小 ,有的消失。大部分患者痛疼消失或明显减轻。结论 动脉灌注化疗对于不适宜手术的晚期胰腺癌或手术未能切除者 ,是值得选择的较好治疗方法 ,可明显提高患者生存质量及生存期。
Objective To investigate the therapeutic effect of arterial chemotherapy on advanced pancreatic cancer. Methods Seventy-eight patients with advanced pancreatic cancer were infused with 5-Fu, epirubicin and cisplatin by femoral artery puncture and selective arterial infusion for 1-2 months intermittently for 1-3 months. Jaundice surgery biliary drainage, including chemotherapy in 12 cases. Results The survival time ranged from 3 to 36 months, and the median survival time was 9.8 months. Most of the tumors were reduced and some disappeared. Most patients with pain disappeared or significantly reduced. Conclusion Arterial infusion chemotherapy is an appropriate treatment for advanced pancreatic cancer or surgical unresectable surgery, which can significantly improve the quality of life and survival of patients.