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D-norgestrel 1 has been synthesizedfrom an optically active synthon 3 whichwas prepared from 13-ethyl-8, 14-seco ster-oid 2 by microbial asymmetric reductiond,Optically active synthon 4 obtained fromthe cyclization of the symmetric triketone
D-norgestrel 1 has been synthesized from an optically active synthon 3 which was prepared from 13-ethyl-8, 14-seco ster-oid 2 by microbial asymmetric reductiond, Optically active synthon 4 obtained from the cyclization of the symmetric triketone