前报已证明小鼠~(60)Co—γ射线照射后小肠粘膜及脾DNA合成很快发生抑制,这种抑制是通过什么机制发生的呢?文献报告不一,有人报告X射线照射后大鼠脾重和DNA含量明显减少,而cAMP含量明显升高;夏寿莹等报告DNA合成减少主要是由于TdR激酶的抑制,而TdR激酶的抑制程度与cAMP浓度成正比。本文采用放射免疫方法测定组织中cAMP(环磷酸腺苷) Previous reports have proved that mice 60Co-γ-ray irradiation of intestinal mucosa and spleen DNA synthesis soon after the suppression of this mechanism by what mechanism? The literature reports vary, it was reported after the large X-ray irradiation Spleen weight and DNA content decreased significantly, while cAMP content was significantly increased; Xia Shouying et al reported DNA synthesis decreased mainly due to inhibition of TdR kinase, and TdR kinase inhibition is proportional to the concentration of cAMP. In this paper, radioimmunoassay method for determination of cAMP (cyclic AMP)