在辐射损伤早期诊断以及辐射防护剂评定等工作中,染色体畸变分析即细胞遗传学的方法,由于其灵敏和可靠而受到普遍的重视。但在染色体标本制备以及观察、分析的自动化尚未普及时,现有的中期和后期染色体分析方法的效率仍嫌不高。为此,Heddle建议用简便而迅速的方法,即检查骨髓细胞微核率来衡量染 In the early diagnosis of radiation injury and the evaluation of radiation protection agents, chromosome aberration analysis (Cytogenetics) has received widespread attention because of its sensitivity and reliability. However, when the automation of chromosome preparation and observation and analysis has not been popularized, the efficiency of the existing mid- and late-stage chromosome analysis methods is still not high. For this reason, Heddle recommends using a simple and rapid method, that is, checking the micronucleus rate of bone marrow cells to measure staining.