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评价SPECT/CT同机融合图像在肺癌单发骨转移瘤定性诊断中的价值。选择196例全身骨显像表现为单发异常放射性核素分布的肺癌患者行骨病变部位CT扫描。由2名核医学科医师对全身骨扫描、SPECT/CT同机融合图像分别做出诊断,诊断分为肺癌骨转移、良性病变,诊断结果分别于最终诊断比较。196例患者,最终诊断骨转移瘤112例,全身骨显像检出89例,SPECT/CT融合显像检出106例。SPECT/CT融合显像探测骨转移瘤的敏感性、特异性及准确性分别为94.6%(106/112)、92.9%(78/84)、93.9%(184/196),明显高于全身骨显像的敏感性79.5%(89/112),特异性78.6%(78/84)、准确性79.1%(155/196)(χ2=11.25,P<0.05;χ2=7.00,P<0.05;χ2=18.35,P<0.05)。在对肺癌单发骨病灶是否为转移的鉴别诊断方面,SPECT/CT融合显像可以提供更多的信息,可以明显提高肺癌单发骨转移瘤的诊断准确率。
To evaluate the value of SPECT / CT fusion imaging in the qualitative diagnosis of single bone metastases of lung cancer. 196 cases of bone scintigraphy were selected for CT scan of bone lesion in patients with lung cancer with single radionuclide distribution. Two nuclear medicine physicians made a diagnosis of whole body bone scintigraphy and SPECT / CT fusion imaging respectively. The diagnosis was divided into bone metastases of lung cancer and benign lesions, and the diagnostic results were compared respectively in the final diagnosis. One hundred and sixty-six patients were diagnosed as bone metastases in 112 cases, 89 cases were detected by whole body bone imaging and 106 cases were detected by SPECT / CT fusion imaging. The sensitivity, specificity and accuracy of SPECT / CT fusion imaging in detection of bone metastases were 94.6% (106/112), 92.9% (78/84) and 93.9% (184/196), respectively, which were significantly higher than those of whole body bone Imaging sensitivity was 79.5% (89/112), specificity was 78.6% (78/84), accuracy was 79.1% (155/196) (χ2 = 11.25, P <0.05; χ2 = 7.00, P <0.05; = 18.35, P <0.05). SPECT / CT fusion imaging can provide more information on the differential diagnosis of single bone lesions in lung cancer, which can significantly improve the diagnostic accuracy of single bone metastases of lung cancer.