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为考核成都地区学龄前儿童自１９９２ 年新生儿普种乙型肝炎血源疫苗后的乙型肝炎（乙肝）感染情况和免疫水平，同时调查该地区丙型肝炎（丙肝）的流行情况，采用ＥＬＩＳＡ 法对９８５ 例标本的乙型肝炎指标（抗－ＨＢｓ、ＨＢｓ－Ａｇ）和丙型肝炎指标（抗－ＨＣＶ）进行了检测。结果：与免疫前相比，免疫后０～７ 岁社区儿童ＨＢｓ－Ａｇ 阳性率降至０．８９％ ，疫苗保护率为９１．３８％ 。免疫后０～７岁各年龄组儿童抗－ＨＢｓ 阳性率在５２％ 与１００％ 之间，随年龄增加，抗－ＨＢｓ 阳性率下降，但各年龄组ＨＢｓ－Ａｇ 阳性率并未随年龄增加而增加，说明乙型肝炎血源疫苗控制乙肝效果好。乙肝血源疫苗在患病儿童中效果较差，尚需进一步研究。丙肝抗体阳性率在社区儿童中为１．１８％ ，患病儿童中为３．１７％ ，表明成都是一丙肝流行区，可能存在母婴传播及幼龄儿童间传播的途径。
In order to assess the hepatitis B (hepatitis B) infection status and immunization status of preschool children in Chengdu since 1992 after the hepatitis B vaccine was popularized, and to investigate the prevalence of hepatitis C (hepatitis C) in this area by ELISA Methods 988 specimens of hepatitis B (anti-HBs, HBs-Ag) and hepatitis C index (anti-HCV) were detected. Results: Compared with pre-immunization, the positive rate of HBs-Ag in children aged 0-7 years after immunization was 0.89%, and the vaccine protection rate was 91.38%. The positive rate of anti-HBs in children aged 0-7 years after immunization was between 52% and 100%. With the increase of age, the positive rate of anti-HBs decreased, but the positive rate of HBs-Ag in each age group did not increase with age Increase, indicating that Hepatitis B blood vaccine control effect of hepatitis B is good. Heparin blood vaccine in children with poor results, still need further study. The positive rate of hepatitis C antibody was 1.18% among community children and 3.17% among sick children, indicating that Chengdu is a hepatitis C epidemic area and there may be a way for mother-to-child transmission and transmission among young children.