Clavuridins A and B, two new trinor-guaiane sesquiterpenes isolated from the Xisha soft coral Clavul

来源 :Chinese Journal of Natural Medicines | 被引量 : 0次 | 上传用户:ejianhuang
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In the present study, two new trinor-guaiane sesquiterpenes, named clavuridins B(1), and A(2), along with three known sesquiterpenes(3-5), were isolated from the Xisha soft coral Clavularia viridis. Their structures and absolute configurations were determined on the basis of spectroscopic analysis, X-ray diffraction analysis with Cu Kα radiation and by comparison with related model compounds. Compounds 1 and 3–5 were evaluated for their cytotoxic activity. In the present study, two new trinor-guaiane sesquiterpenes, named clavulaidins B (1), and A (2), along with three known sesquiterpenes (3-5), were isolated from the Xisha soft coral Clavularia viridis. Their structures and absolute configurations were determined on the basis of spectroscopic analysis, X-ray diffraction analysis with Cu Kα radiation and by comparison with model compounds. Compounds 1 and 3-5 were evaluated for their cytotoxic activity.
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