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目的:分析氨氯地平联合厄贝沙坦应用于高血压合并糖尿病治疗中的效果。方法:随机选取我社区中心诊治的80例高血压合并糖尿病患者,随机分为观察组与对照组,各40例,观察组予氨氯地平联合厄贝沙坦治疗,对照组予厄贝沙坦治疗,比较两组患者的治疗效果。结果:观察组降压疗效优于对照组,组间比较,差异具有统计学意义(P<0.05)。观察组尿白蛋白排泄率(UAER)下降幅度大于对照组,两组比较差异具有统计学意义(P<0.05)。观察组血肌酐及空腹血糖明显降低,与对照组比较,差异具有统计学意义(P<0.05)。结论:采用氨氯地平联合厄贝沙坦治疗高血压合并糖尿病,疗效显著。
Objective: To analyze the effect of amlodipine combined with irbesartan in the treatment of hypertension and diabetes mellitus. Methods: Eighty hypertensive patients with diabetes mellitus diagnosed and treated in our community center were randomly selected and randomly divided into observation group and control group, 40 cases in each group. The observation group was treated with amlodipine combined with irbesartan, while the control group received irbesartan Treatment, the treatment effect of two groups of patients were compared. Results: The antihypertensive efficacy of the observation group was better than that of the control group. The differences between the two groups were statistically significant (P <0.05). The decrease of urinary albumin excretion rate (UAER) in the observation group was larger than that of the control group, the difference was statistically significant (P <0.05). The serum creatinine and fasting blood glucose in the observation group were significantly lower than those in the control group (P <0.05). Conclusion: Amlodipine combined with irbesartan in the treatment of hypertension with diabetes mellitus has a significant effect.