论文部分内容阅读
采用放免法联合测定了６０例慢性肺心病急性加重期（简称肺心病）患者血、尿β２－微球蛋白（β２－－ＭＧ）尿白蛋白（Ａｌｂ）尿ＩｇＧ和尿Ｔａｍｍ－Ｈｏｒｓｆａｌ蛋白（ＴＨＰ）水平，并同时测定了血清尿素氮（ＢＵＮ）和肌酐（Ｃｒ）。结果显示，肺心病患者血、尿β２－ＭＧ，尿Ａｌｂ，尿ＩｇＧ水平显著高于正常人（Ｐ＜０．００１），轻中重三组间也有显著差异（Ｐ＜０．００１）；他们的阳性率（６３．３３％，６６．６７％，５５％，５１．６７％），显著高于ＢｕＮ（１０％）和Ｃｒ（２１．６７％）的阳性率（Ｐ＜０．０１）；尿ＴＨＰ在轻度患者明显升高（Ｐ＜０．０５），在重度患者显著下降（Ｐ＜０．００１）。结果表明肺心病患者的肾功能均有不同程度损害，放免法测定肾功能是早期而敏感的指标，可早期发现肺心病患者的肾功能损害并判断其损害程度及部位
60 patients with acute exacerbation of chronic cor pulmonale were enrolled in this study. The urinary albuminuria (Alb) and urine Tamm-Horsfal protein (THP ) Levels were measured and serum urea nitrogen (BUN) and creatinine (Cr) were measured simultaneously. The results showed that blood, urine β2-MG, urinary Alb, urinary IgG levels in patients with pulmonary heart disease were significantly higher than those in normal people (P <0.001), and there were significant differences among light, medium and heavy groups (P <0.001) (63.33%, 66.67%, 55%, 51.67%) was significantly higher than that of BuN (10%) and Cr (21.67%) (P <0.01). Urine THP was significantly higher in mild patients (P <0.05) and significantly lower in severe patients (P <0.001). The results showed that patients with pulmonary heart disease have varying degrees of renal damage, radioimmunoassay is an early and sensitive indicator of renal function, early detection of pulmonary heart disease in patients with renal damage and determine the extent of injury and site