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2007年《欧洲慢性鼻窦炎鼻息肉诊疗指南》(EPOS-2007)推荐低剂量、长期使用大环内酯类药物作为慢性鼻及鼻窦炎(chronic rhinosinusitis,CRS)的治疗方案受到广泛的关注[1]。越来越多的证据显示大环内酯类药物不仅通过抑菌发挥作
In 2007, the European Guide to the Treatment and Treatment of Chronic Sinusitis and Nasal Polyps (EPOS-2007) recommended that low-dose, long-term use of macrolides as a treatment for chronic rhinosinusitis (CRS) has received extensive attention [1 ]. More and more evidences show that macrolides not only work by inhibiting bacteria