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3例患者(例1女,52岁,有甲型肝炎史;例2女,64岁;例3女,61岁)均因慢性胃炎给予摩罗丹(浓缩丸)16丸口服、3次/d。例1无合并用药,例2合并使用雷贝拉唑钠肠溶片,例3合并使用雷贝拉唑钠肠溶片及瑞巴派特片。例1、例2、例3分别在服用摩罗丹(浓缩丸)27、22、19 d后出现肝功能异常,丙氨酸转氨酶(ALT)均升高>5倍参考值上限,例2、例3伴胆红素升高。例1、例2、例3均立即停用摩罗丹(浓缩丸),分别在给予保肝治疗18、22、24 d后肝功能恢复正常。“,”Three patients (patient 1, a 52-year-old female, with a history of hepatitis; patient 2, a 64-year-old female; patient 3, a 61-year-old female) were all treated with n morodan concentrated pill (16 pills, thrice daily for all) for chronic gastritis. In patient 1, there were no combined drugs; in patient 2, sodium rabeprazole enteric-coated tablets were also used; in patient 3, sodium rabeprazole enteric-coated tablets and rebamipide tablets were combined. Patient 1, patient 2, and patient 3 developed abnormal liver function after 27, 22, and 19 days of n morodan concentrated pill administration, respectively. Their alanine aminotransferase (ALT) increased by more than 5 times the upper limit of the reference value, accompanied by elevated bilirubin in patient 2 and patient 3. All the 3 patients were stopped to use n morodan concentrated pill immediately. After 18, 22, and 24 days of liver-protective treatments, the liver function of patient 1, patient 2, and patient 3 returned to normal, respectively.n