A New Phenolic Glucoside from Paeonia lactiflora

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Objective To study the chemical constituents from EtOAc extracts of Paeonia lactiflora.Methods Compounds were isolated by various chromatographic techniques and structures were elucidated on the basis of spectral analysis.Results Seventeen compounds were obtained and their structures were identified as 1,2,6-benzenetriol-1-O-α-D-glucoside(1),paeoniflorin(2),4-methylpaeoniflorin(3),albiflorin(4),paeonidanin(5),benzoylpaeoniflorin(6),4-methylbenzoylpaeoniflorin(7),benzoylalbiflorin(8),paeonidanin A(9),galloylalbiflorin(10),debenzoylalbiflorin(11),4’,5-dihydroxyflavanone-7-O-β-D-glucoside(12),5,7-dihydroxy flavanone-4’-O-β-D-glucoside(13),(+)-catechin(14),gallic acid(15),vanillic acid(16),and 1,2,3-benzenetriol(17).Conclusion Compound 1 is a new compound named paeoniphenoside.Compounds 12 and 13 are firstly obtained from genus Paeonia L.,and compounds 5 and 9 are isolated from P.lactiflora for the first time. Objective To study the chemical constituents from EtOAc extracts of Paeonia lactiflora. Methods Compounds were isolated by various chromatographic techniques and structures were elucidated on the basis of spectral analysis. Results Seventeen compounds were obtained and their structures were identified as 1,2,6-benzenetriol -1-O-α-D-glucoside (1), paeoniflorin (2), 4-methylpaeoniflorin (3), albiflorin (4), paeonidanin (5), benzoylpaeoniflorin (6), 4-methylbenzoylpaeoniflorin (7) and benzoylalbiflorin 8), paeonidanin A (9), galloylalbiflorin (10), debenzoylalbiflorin (11), 4 ’, 5-dihydroxyflavanone-7- O -beta-D-glucoside (+) - catechin (14), gallic acid (15), vanillic acid (16), and 1,2,3-benzenetriol named paeoniphenoside. Compounds 12 and 13 arereed obtained from genus Paeonia L., and compounds 5 and 9 are isolated from P. lactiflora for the first time.
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