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术中放射治疗(IORT)可对明视下的瘤床行单次大剂量放射,同时将重要的正常结构排除或遮挡在治疗区域之外。一般用直线加速器产生的电子束进行。区域视野清晰,电子束锥体放置容易的头颈部肿瘤适合这种方法,另一些肿瘤比如颅底肿瘤其部位不易到达,则可通过后载式导管行高放射量率短距离治疗。已有IORT对晚期或复发肿瘤产生功效的报道,但几乎没有关于并发症发病率和死亡率的研究。由于作者主要从事晚末期肿瘤的治疗,患者对IORT的耐受性是重要问题,也是本文的研究目的。
Intraoperative radiotherapy (IORT) can perform a single high-dose radiation on the tumor bed under photopic vision, while excluding or shielding important normal structures from the treatment area. It is usually done with an electron beam generated by a linear accelerator. Clear view of the area, electron beam cones easy to place head and neck tumors suitable for this method, and other tumors such as skull base tumors difficult to reach the site, you can use the rear-loading catheter for high radiation rate short-distance treatment. There have been reports of IORT’s efficacy in advanced or recurrent tumors, but there have been few studies of morbidity and mortality. Since the authors are mainly engaged in the treatment of late-stage tumors, the patient’s tolerance to IORT is an important issue and the purpose of this study.