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本研究采用配对设计的方法，对接触组和对照组人员分别测定了血和尿中镉、钙和β２－微球蛋白（β２－ＭＧ）含量，并测定尿Ｎ－乙酰－β－Ｄ－氨基葡萄糖苷酶（ＮＡＧ）活性和总蛋白含量。结果显示，接触组尿镉、钙、β２－ＭＧ、总蛋白含量和ＮＡＧ活性及血镉含量都高于对照组。尿ＮＡＧ活性与血和尿中镉、钙、β２－ＭＧ和总蛋白含量均呈正相关，表明尿ＮＡＧ是监测镉引起肾损害的敏感指标之一。
In this study, the method of paired design was used to detect the content of cadmium, calcium and β2-microglobulin (β2-MG) in blood and urine of the contact group and the control group, respectively, and the levels of urine N-acetyl-β-D-amino Glucosidase (NAG) activity and total protein content. The results showed that the content of urinary cadmium, calcium, β2-MG, total protein, NAG activity and blood cadmium in the exposure group were higher than those in the control group. The urinary NAG activity was positively correlated with the levels of cadmium, calcium, β2-MG and total protein in blood and urine, indicating that urinary NAG is one of the sensitive indicators for monitoring cadmium-induced renal damage.