已发现 3 2 %～ 80 %的哮喘患者有胃食管反流 ,尽管这两种疾病有联系 ,但确定它们之间的因果关系是困难的。已知哮喘患者因有胸腹压力梯度增加而促进反流 ,另一方面有人提出有两种机制胃食管反流可造成或加重哮喘 ,即吸入微量胃液以及迷走神经介导的食管支气管反射。本文目的是 It has been found that 32% to 80% of asthmatics have gastroesophageal reflux and although the two diseases are linked, it is difficult to determine the causal relationship between them. Asthma patients are known to promote reflux because of an increased pressure gradient in the thorax and abdomen. On the other hand, two mechanisms have been proposed for gastroesophageal reflux, which can cause or exacerbate asthma, ie, inhaled trace gastric fluid and vagal-mediated esophageal bronchial reflex. The purpose of this article is