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药物滥用是全世界面临的严重问题。由药物滥用造成的个人和公众健康损害、道德沧落、意外事故、刑事犯罪、恐布主义等社会危害令人触目惊心。在国际公认的滥用药物类型中,镇静催眠药被列入国际精神药物公约管制。镇静催眠药是抑制中枢神经系统引起镇静和催眠的药物,其种类多,数量大,药理作用广泛。一般镇静催眠药小剂量的镇静,中剂量催眠,大剂量麻醉,有的还有抗惊厥,抗精神病作用,是临床治疗中应用广泛,不可缺少的药物。传统的镇静催眠药有巴比妥类(常用的有苯巴比妥、异戊巴比妥
Drug abuse is a serious problem facing the world. Personal and public health damage caused by drug abuse, moral abuse, accidents, criminal offenses and phobia are all alarming. Among the internationally recognized types of drug abuse, sedatives and hypnotics are covered by the International Convention on Psychotropic Substances. Sedative hypnotics are drugs that inhibit the central nervous system caused by sedation and hypnosis, its variety, large number, broad pharmacological effects. Generally sedative hypnotic small dose of sedation, hypnotic dose, high-dose anesthesia, and some anticonvulsant, anti-psychotic effect, is widely used in clinical treatment, indispensable drugs. Traditional sedation hypnotics have barbiturates (commonly used phenobarbital, amobarbital