自从胰岛素问世后,糖尿病患者得到了较满意的治疗,但截至六十年代为止,还没有一个理想的指标来监测糖尿病的长期疗效。以往把血糖和尿糖作为糖尿病的控制指标,但血糖主要反映采血当时的糖代谢;饭前、饭后血糖也只反映较短时间内的糖代谢,不宜作为糖尿病的长期控制指标。1969年Rahhar等观察到糖尿病患者糖化血红 Since the advent of insulin, patients with diabetes have been treated more satisfactorily, but as of the 1960s, there is no ideal indicator to monitor the long-term efficacy of diabetes. In the past, blood sugar and urine sugar as a control index of diabetes, but blood glucose mainly reflects the blood sugar metabolism; pre-and postprandial blood glucose also reflects only a short period of glucose metabolism, should not be used as a long-term control of diabetes indicators. In 1969, Rahhar et al observed glycated blood red blood cells in diabetic patients