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冲剂是应用较广泛的一种中药制剂,由于中药饮片经提取后添加辅料制成的冲服剂,在生产程中有时发生清膏浓缩易焦化,制粒时软材不易过筛,成品颗粒色泽不匀,粒度检查不符合规定等问题,为此对冲剂工艺进行分析,结果认为先将稠膏与乙醇(10∶1)混合,并将湿润剂乙醇改为水,因水易于较快地渗入糖粉与糊精中,并增加了粘性,而较易制成适宜的软材,基本上克服了颗粒色泽不匀,细粉较多现象。
The granules are widely used as a Chinese medicine preparation. Since the Chinese medicine pieces are extracted and added with auxiliary materials made of blunt agents, it sometimes occurs during the production process that the concentrated extract is easily coked, and when the granulation is carried out, the soft material is not easily sifted and the finished product is not colored. Uniformity, particle size check does not meet the requirements and other issues, for this analysis of the blister process, the results that the thick paste and ethanol (10:1) were mixed, and the humectant ethanol was changed to water, because water tends to infiltrate the sugar faster Powder and dextrin, and increase the viscosity, and easier to make a suitable soft material, basically to overcome the particles uneven color, fine powder more phenomenon.