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近年来,很多人报导烃氟类气溶胶助喷剂是一种心血管系统的毒物,它可引起室性心动过速、心动徐缓、全身性动脉血压降低以及直接抑制心肌收缩力。也有发生突然死亡的报导。本文研究目的在于评价吸入二氟二氯甲烷(F-12)助喷剂,对心肌损害的持久性和损害消失的速度。实验采用体重2.5～5.0公斤的雌性猫,吸入37%F-12-21%O_2-42%N_2的混合气体4分钟,并在吸入前和吸入停止后的不同时间给猫静脉注射肾
In recent years, many people report that hydrocarbon fluoride aerosol propellant is a cardiovascular system poison, it can cause ventricular tachycardia, bradycardia, systemic arterial pressure and direct inhibition of myocardial contractility. There have also been reports of sudden deaths. The purpose of this study was to evaluate the persistence of myocardial damage and the rate at which lesions disappear when inhaled difluorodichloromethane (F-12) spray aid. In the experiment, female cats weighing 2.5-5.0 kg were inhaled with a mixed gas of 37% F-12-21% O 2-42% N 2 for 4 minutes. Cats were intravenously injected with the kidney at different times before inhalation and after inhalation