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目的研究胃癌患者体内血清微量元素和幽门螺杆菌的变化关系。方法对胃癌、慢性胃炎患者和正常人(对照组)进行血清6种微量元素和幽门螺杆菌感染的测定。结果胃癌组镁(Mg)、钙(Ca)、铜(Cu)、锌(Zn)明显低于对照组,分别为Mg(0.71±0.15)mmol/L与(0.97±0.26)mmol/L,Ca(1.68±0.28)mmol/L与(2.03±0.31)mmol/L,Cu(12.27±5.91)mmol/L与(16.57±3.55)mmol/L,Zn(16.18±4.77)mmol/L与(21.78±7.37)mmol/L;胃癌患者Hp的感染率为71.4%,对照组的Hp感染率为27.3%,两组差异有显著意义(χ2=6.201,P=0.013)。结论血清微量元素变化和幽门螺杆菌感染可能与胃癌的发生有关。
Objective To study the relationship between serum trace elements and Helicobacter pylori in gastric cancer patients. Methods The serum levels of 6 trace elements and Helicobacter pylori in gastric cancer, chronic gastritis patients and normal people (control group) were measured. Results The levels of Mg, Ca, Cu and Zn in gastric cancer group were significantly lower than those in control group (0.71 ± 0.15 mmol / L and 0.97 ± 0.26 mmol / L, respectively) (1.68 ± 0.28) mmol / L and (2.03 ± 0.31) mmol / L Cu (12.27 ± 5.91) mmol / L and (16.57 ± 3.55) mmol / L and Zn 7.37) mmol / L. The prevalence of Hp infection was 71.4% in gastric cancer patients and 27.3% in control subjects. There was significant difference between the two groups (χ2 = 6.201, P = 0.013). Conclusion Serum trace element changes and Helicobacter pylori infection may be related to the occurrence of gastric cancer.