目的:探讨双歧杆菌三联活菌胶囊联合多潘立酮治疗功能性胃肠病的临床疗效及对患者消化功能的影响。方法:选择2018年1月至2019年12月温岭市中医院治疗的功能性胃肠病患者126例为研究对象，采用随机数字表法分为观察组、对照组各63例。对照组给予多潘立酮治疗，观察组联合双歧杆菌三联活菌胶囊治疗。对两组患者的临床疗效、症状评分、消化功能指标、不良反应发生率等进行统计分析。结果:观察组总有效率为90.48%(57/63)，高于对照组的为76.19%(48/63)，组间差异有统计学意义(χn 2＝4.629，n P＝0.031)。治疗后观察组患者的症状评分包括恶心呕吐、腹泻、嗳气、便秘评分均低于对照组，差异均有统计学意义(n t＝5.575、5.235、4.866、4.958，n P＝0.000、0.000、0.000、0.000)。治疗后观察组患者的消化功能指标包括胰淀粉酶(PAMY)、胰高血糖素(GLU)、胃泌素(GAS)水平均低于对照组，差异均有统计学意义(n t＝7.506、4.256、4.822，n P＝0.000、0.000、0.000)。治疗期间观察组、对照组不良反应发生率分别为15.87%(10/63)、9.52%(6/63)，组间差异无统计学意义(χn 2＝1.145，n P＝0.285)。n 结论:双歧杆菌三联活菌胶囊联合多潘立酮治疗功能性胃肠病的临床疗效显著，能够改善患者的各项胃肠道相关症状，改善患者的消化功能，治疗安全性良好，值得临床推荐。“,”Objective:To study the clinical effect of Bifidobacterium capsule combined with domperidone in the treatment of functional gastrointestinal diseases and its influence on the digestive function of patients.Methods:From January 2018 to December 2019, 126 patients with functional gastrointestinal diseases treated in Wenling Hospital of Traditional Chinese Medicine were collected in this study.According to the random number table method, the patients were divided into observation group and control group, with 63 cases in each group.The control group was treated with domperidone, and the observation group was given domperidone combined with Bifidobacterium capsule.The clinical effect, symptom score, digestive function index and adverse reaction of the two groups were compared.Results:The total effective rate of the observation group was 90.48%(57/63), which was higher than that of the control group(76.19%)(χn 2=4.629, n P=0.031). After treatment, the scores of nausea and vomiting, diarrhea, belching and constipation in the observation group were lower than those in the control group, the differences were statistically significant between the two groups(n t=5.575, 5.235, 4.866, 4.958, n P=0.000, 0.000, 0.000, 0.000). After treatment, the levels of amylase(PAMY), glucagon(GLU) and gastrin(GAS) in the observation group were lower than those in the control group, the differences were statistically significant between the two groups(n t=7.506, 4.256, 4.822, n P=0.000, 0.000, 0.000). During treatment, the incidences of adverse reactions in the observation group and the control group were 15.87%(10/63) and 9.52%(6/63), respectively, the difference was statistically significant between the two groups(χn 2=1.145, n P=0.285).n Conclusion:Bifidobacterium capsule combined with domperidone has significant clinical effect in the treatment of functional gastrointestinal diseases, which can improve the gastrointestinal symptoms, improve the digestive function of patients, and has good safety.It is worthy of clinical recommendation.