Aryne is reactive intermediate in which a π bond is formed by overlapping two σ-orbitals on the ortho position of an arene.With the development of 2-(trimethy
The noble transition-metal (i.e., Pd, Ru, Rh, and Ir) catalysts play a dominant role in the stage of inert chemical bond functionalization.Our efforts are mainl
We have established Lewis acid-catalyzed allylation, cyanation and azidation of 1,4-disubstituted 1,4-epoxy-1,4-dihydronaphthalenes to afford the corresponding
Synthetic studies connected with the synthesis of telcagepant via the corresponding achiral part Ⅲ and chiral part Ⅳ will be discussed.The achiral part was co