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目的 :对质子泵抑制剂三联与铋剂三联抗幽门螺杆菌根治率进行比较及对两类方法做经济评价。方法 :对经 1 4 C呼气试验测定幽门螺杆菌阳性的患者 ,经质子泵抑制剂三联或铋剂三联抗幽门螺杆菌治疗 ,复查1 4 C呼气试验测定幽门螺杆菌 ,了解其根治率 ;根据根治率及药物做出经济评价。结果 :质子泵抑制剂三联组抗幽门螺杆菌根治率为 91% ,而铋剂三联组抗幽门螺杆菌根治率为 72 % ,治疗费用质子泵抑制剂三联组高于铋剂三联组。结论 :质子泵抑制剂三联抗幽门螺杆菌根治率高于铋剂三联 ( P<0 .0 1) ,但治疗的成本 /效果比亦高于铋剂三联
OBJECTIVE: To compare the cure rates of triple anti-Helicobacter pylori proton pump inhibitor and bismuth anti-helicobacter pylori and to evaluate the two methods. Methods: Helicobacter pylori positive patients were determined by 14C breath test. The patients were treated with proton pump inhibitor triple or bismuth in combination with anti-Helicobacter pylori. The helicobacter pylori was determined by 1 4 C breath test and the cure rate ; According to the cure rate and economic evaluation of drugs. Results: The anti-Helicobacter pylori radical cure rate was 91% in the triad of proton pump inhibitor and 72% in anti-Helicobacter pylori in the bismuth triad. The cost of the proton pump inhibitor triple therapy was higher than that of the bismuth triple therapy. Conclusion: The proton pump inhibitor triple anti-Helicobacter pylori cure rate is higher than the bismuth triple (P <0.01), but the treatment cost / effect ratio is also higher than the bismuth triad