高渗性非酮症糖尿病昏迷是糖尿病的严重并发症,据报道其死亡率在10%~70%,最近报道仍在20%~30%[1]。在高渗状态未纠正时死亡率可达26.67%,其死亡主要原因伴随感染、休克、消化道出血、脑血管意外、败血症、肾衰等,同时与高渗状态纠正早晚亦有一定关系[2]。临床常见治疗为补液、纠正电解质紊乱及防治诱因,治疗合并症,但由于病情变化快速、休克不易纠正或出现多器官功能衰竭, Hyperosmolar nonketotic diabetic coma is a serious complication of diabetes and is reported to have a mortality rate of 10% to 70%, with a recent reported 20% to 30%. In the hypertonic state uncorrected, the death rate was up to 26.67%. The main causes of death were associated with infection, shock, gastrointestinal bleeding, cerebrovascular accident, sepsis, renal failure and so on, ]. Common clinical treatment of rehydration, electrolyte imbalance and prevention of incentives to cure complications, but because of rapid changes in condition, shock is not easy to correct or appear multiple organ failure,