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目的:研究刺楸树皮的化学成分,为阐明其活性成分提供依据。方法:采用80%乙醇进行提取,硅胶柱色谱、ODS柱色谱及高效液相制备进行分离纯化,波谱分析(核磁共振氢谱、碳谱和质谱)确定结构。结果:分离鉴定了7个化合物,分别为3-O-α-L-阿拉伯糖-28-O-α-L-鼠李糖-(1→4)-O-β-D-葡萄糖-(1→6)-O-β-D-葡萄糖基-常春藤皂苷元酯(Ⅰ),刺楸皂苷I(Ⅱ),3-O-α-L-鼠李糖-(1→2)-O-α-L-阿拉伯糖-28-O-β-D-葡萄糖-(1→6)-O-β-D-葡萄糖常春藤皂苷元酯(Ⅲ),刺楸皂苷B(Ⅳ),丁香树脂醇双葡萄糖苷(Ⅴ),2-甲氧基对苯二酚4-O-[6-O-(4-O-α-L-鼠李糖基)-紫丁香基]-β-D-吡喃葡萄糖(Ⅵ),紫丁香苷(Ⅶ)。结论:化合物Ⅰ,Ⅲ,Ⅴ,Ⅵ为首次从本属植物中分得。
Objective: To study the chemical constituents of bark of Catalpa bungei, and to provide basis for elucidating its active ingredients. Methods: The constituents were isolated and purified by 80% ethanol extraction, silica gel column chromatography, ODS column chromatography and HPLC. The structures were confirmed by spectral analysis (1H NMR, GC and MS). Results: Seven compounds were isolated and identified as 3-O-α-L-arabinose-28-O-α-L-rhamnose- (1 → 4) -O-β-D-glucose- → 6) -O-β-D-glucosyl-Ivy saponin I, II, 3-O-α-L-rhamnose- α-L-arabinose-28-O-β-D-glucose- (1 → 6) -O-β-D-glucose ivy saponin (Ⅲ) (Ⅴ), 2-methoxy hydroquinone 4-O- [6-O- (4-O-α-L-rhamnosyl) Glucose (Ⅵ), syringin (Ⅶ). Conclusion: Compounds Ⅰ, Ⅲ, Ⅴ and Ⅵ were isolated from this genus for the first time.