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目的了解糖尿病群体中抑郁症的患病率,探讨糖尿病与抑郁症之间的关系及影响因素。方法随机选取256例2型糖尿病患者,根据汉密尔顿抑郁表-24项评分,将患者分为两组:一组为糖尿病抑郁症组,另一组为糖尿病非抑郁症组,比较两组患者的体重指数、糖化血红蛋白、空腹血糖、餐后2 h血糖、糖尿病并发症及文化程度等。结果糖尿病合并抑郁症患者发病率为32.4%(83/256)。两组患者比较,抑郁症组vs非抑郁症组空腹血糖(9.6±2.3)mmol/L vs(7.5±1.5)mmol/L※,餐后2 h血糖(14.2±5.3)mmol/L vs(11.2±1.9)mmol/L※,体重指数(BMI)(27.2±2.7)kg/m2vs(23.1±3.1)kg/m2※,文化程度初中以下学历:44.58%vs 20.23%。(※表示P<0.05)。结论抑郁症在糖尿病人群中有较高的患病率,糖尿病患者的病情得不到良好的控制,更容易促进出现并发症的发生和发展。
Objective To understand the prevalence of depression in diabetic population and explore the relationship between diabetes mellitus and depression and its influencing factors. Methods A total of 256 patients with type 2 diabetes mellitus were randomly divided into two groups according to the Hamilton Depression Scale-24 score: one was diabetes mellitus depression group and the other was diabetes non-depression group. The body weight Index, glycosylated hemoglobin, fasting blood glucose, postprandial blood glucose 2 h, diabetic complications and educational level. Results The incidence of diabetes mellitus with depression was 32.4% (83/256). The fasting blood glucose (9.6 ± 2.3) mmol / L vs (7.5 ± 1.5) mmol / L * and postprandial 2 h glucose (14.2 ± 5.3) mmol / L vs (11.2 ± 1.9) mmol / L ※, BMI (27.2 ± 2.7) kg / m2vs (23.1 ± 3.1) kg / m2 ※, education level below junior high school education: 44.58% vs 20.23%. (※ means P <0.05). Conclusions Depression has a high prevalence in diabetic population. The condition of diabetic patients is not well controlled and the occurrence and development of complications are more likely to be promoted.