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[目的]探讨急性心肌梗死患者合并肾功能减退的临床特点;比较肌酐(Creatinine)以及肌酐清除率(Creatinine clearance)两种评价肾功能方法的差异。[方法]回顾性收集发病24h内入院的急性心肌梗死患者的病例资料,共198例。入院24h内查血Cr水平,用Cockcroft-Gault(CG)公式计算CCr,分析其中合并肾功能不全患者的临床特点,并比较Cr、CCr判断肾功能的临床差异。[结果]急性心肌梗死患者中合并肾功能减退常见(45.95%),仅以Cr水平判断肾功能会漏诊91.20%的肾功能减退患者,以CCr判断患者肾功能更佳;尤其对于高龄、体质偏小的女性。[结论]使用CCr评价AMI患者肾功能情况,较Cr更具敏感性。
[Objective] To investigate the clinical features of renal dysfunction in patients with acute myocardial infarction (AMI). Creatinine and creatinine clearance were compared to evaluate the difference of renal function. [Methods] A retrospective collection of patients admitted to hospital within 24 hours of acute myocardial infarction patients, a total of 198 cases. The level of serum Cr was measured within 24 hours after admission, and the CCr was calculated by the formula of Cockcroft-Gault (CG). The clinical features of patients with renal dysfunction were analyzed. The clinical differences of renal function between Cr and CCr were compared. [Results] The common renal dysfunction (45.95%) was found in patients with acute myocardial infarction. Judgment of renal function at Cr level would miss 91.20% patients with renal dysfunction, and CCr showed that the patients had better renal function. Especially for the elderly, Small women. [Conclusion] The evaluation of renal function in patients with AMI using CCr is more sensitive than that of Cr.